Man City broke the deadlock through De Bruyne halfway through the first half in what eventually ended up as Arsenal's 3-1 defeat to the defending champions.
Takehiro Tomiyasu tried to play a backpass to Ramsdale but his effort wasn't strong enough. De Bruyne intercepted the ball and lobbed the goalie with a first-time effort.
After the goal, Oleksandr Zinchenko came up to Tomiyasu to console the Japanese.
Tommy went on to have a decent spell before City's second goal which saw Grealish's strike get deflected off the right-back into the net.
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